SCHEMBL1699651

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1699707	0.91	CYP3A4 (0.39)	CYP3A4KMT2AALOX5TP53PTGES
	SCHEMBL15165269	0.89	CYP3A4 (0.41)	CYP3A4KMT2AERAP1PSIP1HSP90AA1
	SCHEMBL1699716	0.89	CYP3A4 (0.49)	CYP3A4KMT2AERAP1PSIP1HSP90AA1
	SCHEMBL15165246	0.89	CYP3A4 (0.41)	CYP3A4KMT2AERAP1PSIP1HSP90AA1
	SCHEMBL1699586	0.89	CYP3A4 (0.49)	CYP3A4KMT2AERAP1PSIP1HSP90AA1
	SCHEMBL1699725	0.89	CYP3A4 (0.49)	CYP3A4KMT2AERAP1PSIP1HSP90AA1
	SCHEMBL15165268	0.89	CYP3A4 (0.41)	CYP3A4KMT2AERAP1PSIP1HSP90AA1
	SCHEMBL1699641	0.86	ERAP1 (0.35)	CYP3A4KMT2AERAP1TACR3SLC6A4
	SCHEMBL1699757	0.83	SLC6A4 (0.36)	KMT2AERAP1TACR3SLC6A4SLC6A3
	SCHEMBL1699579	0.83	SLC6A4 (0.36)	KMT2AERAP1TACR3SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.