Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699516 | 0.84 | PSIP1 (0.30) | — | |
| SCHEMBL10272115 | 0.80 | — | — | |
| SCHEMBL1699447 | 0.78 | — | — | |
| SCHEMBL1699656 | 0.77 | PTGDR2 (0.34) | PTGDR2 | |
| SCHEMBL15093250 | 0.77 | CXCR2 (0.36) | — | |
| SCHEMBL15093539 | 0.76 | KDM4E (0.33) | PTGDR2PTGESALOX5PPARG | |
| SCHEMBL15093536 | 0.74 | PSIP1 (0.32) | — | |
| SCHEMBL15093733 | 0.71 | CXCR2 (0.32) | — | |
| SCHEMBL1699760 | 0.71 | PTGDR2 (0.35) | PTGDR2PPARGPPARA | |
| SCHEMBL15099727 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588450-A1 | NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS | Gilead Sciences, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003497-A1 | NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |