Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 9/20 | 0.34 |
| ▸ | PPARA | Q07869 | 9/20 | 0.34 |
| ▸ | PPARD | Q03181 | 7/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | ALPI | P09923 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699307 | 0.86 | CYP3A4 (0.45) | PTGDR2PPARGCYP3A4DHODH | |
| SCHEMBL27921791 | 0.85 | CTRC (0.35) | PPARGPPARAPPARDDHODHCTRC | |
| SCHEMBL1699571 | 0.84 | PTGDR2 (0.37) | PTGDR2CYP3A4DHODHCTRC | |
| SCHEMBL10271593 | 0.83 | CYP3A4 (0.38) | PTGDR2PPARACYP3A4 | |
| SCHEMBL27903964 | 0.82 | GPR84 (0.39) | PPARGPPARACTRC | |
| SCHEMBL10272102 | 0.82 | PTGDR2 (0.37) | PTGDR2PPARACYP3A4 | |
| SCHEMBL27903955 | 0.81 | CTRC (0.34) | PPARGPPARAPPARDCYP3A4DHODH | |
| SCHEMBL27921885 | 0.80 | ROCK2 (0.39) | DHODHCTRC | |
| SCHEMBL27910427 | 0.80 | PTGS2 (0.38) | PTGDR2PPARGPPARAPTGS1PTGS2 | |
| SCHEMBL27921847 | 0.80 | CYP1A2 (0.39) | PPARGPPARAPPARDCYP3A4DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588450-A1 | NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS | Gilead Sciences, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003497-A1 | NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |