SCHEMBL1699677

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1699681	0.93	CYP3A4 (0.48)	CYP3A4PSIP1ARPTGES2KCNH2
	SCHEMBL15165247	0.92	CYP3A4 (0.39)	CYP3A4PSIP1ARPTGES2ALDH1A1
	SCHEMBL1699524	0.90	CYP3A4 (0.46)	CYP3A4PSIP1ARKCNH2
	SCHEMBL10271608	0.89	CYP3A4 (0.53)	CYP3A4PSIP1PTGES2KCNH2KMT2A
	SCHEMBL1699506	0.88	CYP3A4 (0.52)	CYP3A4PSIP1PTGES2KMT2APPARG
	SCHEMBL1699493	0.88	CYP3A4 (0.52)	CYP3A4PSIP1PTGES2KCNH2KMT2A
	SCHEMBL1699552	0.86	CYP3A4 (0.44)	CYP3A4PSIP1CYP1A2
	SCHEMBL1699749	0.85	CYP3A4 (0.50)	CYP3A4PSIP1ARPTGES2KCNH2
	SCHEMBL1699586	0.85	CYP3A4 (0.49)	CYP3A4PSIP1PTGES2KCNH2KMT2A
	SCHEMBL1699716	0.85	CYP3A4 (0.49)	CYP3A4PSIP1PTGES2KCNH2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.