Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70060 | 0.80 | KDM4E (0.54) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL12247555 | 0.78 | KDM4E (0.52) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL12247553 | 0.78 | KDM4E (0.52) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL27339631 | 0.78 | HSD17B10 (0.58) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL13909062 | 0.76 | KDM4E (0.50) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL10246598 | 0.76 | KDM4E (0.50) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL778962 | 0.76 | KDM4E (0.61) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL5553040 | 0.74 | MAPT (0.50) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2672089 | 0.74 | KDM4E (0.59) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| Acetic Acid SCHEMBL7320116 | 0.73 | HSD17B10 (0.83) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120049-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA, INC. (US) | 2015-08-13 | — | — | WO | disclosed |