Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24680307 | 0.83 | KDM4E (0.43) | KDM1A | |
| SCHEMBL16997043 | 0.83 | KDM4E (0.43) | KDM1A | |
| SCHEMBL24680346 | 0.83 | KDM4E (0.43) | KDM1A | |
| SCHEMBL16997091 | 0.82 | — | — | |
| SCHEMBL18501635 | 0.81 | ACHE (0.36) | KDM1A | |
| SCHEMBL17918915 | 0.77 | KDM1A (0.33) | KDM1A | |
| SCHEMBL27051127 | 0.76 | — | — | |
| SCHEMBL25081326 | 0.75 | ALOX15 (0.31) | — | |
| SCHEMBL24680330 | 0.75 | ALOX15 (0.31) | — | |
| SCHEMBL25081554 | 0.75 | ALOX15 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120049-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA, INC. (US) | 2015-08-13 | — | — | WO | disclosed |