SCHEMBL16997178

SCHEMBL16997178

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc(-c5cccc6c5c5cccc(-c7ccccc7)c5n6-c5ccccc5)cc4)c3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.34
PDE10A Q9Y233 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
AVPR1A P37288 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
ABCG2 Q9UNQ0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16997179 0.98 RXFP1 (0.34) RXFP1PDE10AKDM4EATML3MBTL1
SCHEMBL16997208 0.96 KDM4E (0.35) RXFP1PDE10AKDM4EATML3MBTL1
SCHEMBL16997176 0.95 KDM4E (0.36) RXFP1KDM4EATML3MBTL1MEN1
SCHEMBL22426340 0.91 L3MBTL1 (0.39) RXFP1PDE10AKDM4EATML3MBTL1
SCHEMBL16997237 0.91 RXFP1 (0.33) RXFP1KDM4EATML3MBTL1MEN1
SCHEMBL25654600 0.90 KDM4E (0.35) RXFP1PDE10AKDM4EATML3MBTL1
SCHEMBL22058760 0.89 RXFP1 (0.34) RXFP1KDM4EATML3MBTL1MEN1
SCHEMBL24361773 0.89 KDM4E (0.38) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL25649378 0.88 PDE10A (0.35) RXFP1PDE10AKDM4EATML3MBTL1
SCHEMBL22047900 0.88 KDM4E (0.41) RXFP1KDM4EATML3MBTL1AVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-20200295272-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-09-17 US disclosed
US-10741772-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-08-11 US disclosed
US-9911925-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-9911925-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
EP-2991128-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2017-04-12 EP disclosed
US-20160072078-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-10 US disclosed
US-20160072078-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-10 US disclosed
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-08-13 US disclosed
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1B1, CYP1A1, CRY1 RXFP1 1583/4885PDE10A 3614/4885KDM4E 2931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.