SCHEMBL1699762

SCHEMBL1699762

Nc1ccccc1OP(=O)(Oc1ccccc1N)Oc1ccccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 2/20 0.48
RECQL P46063 1/20 0.48
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
GAA P10253 2/20 0.39
RCE1 Q9Y256 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5334635 0.91 ALDH1A1 (0.46) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL28347236 0.87 ALDH1A1 (0.54) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL28790810 0.87 ALDH1A1 (0.43) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL30118861 0.82 ALDH1A1 (0.52) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL569537 0.82 INPPL1 (0.57) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL10321089 0.82 ALDH1A1 (0.46) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL8089431 0.82 CD44 (0.38) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL28678394 0.80 INPPL1 (0.55) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL28665448 0.80 INPPL1 (0.55) ALDH1A1ADRA2BPTGS1TDP1LMNA
SCHEMBL28687913 0.80 INPPL1 (0.55) ALDH1A1ADRA2BPTGS1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116203093-A Electrochemical microfluidic biochip for amplifying hybridization DNA signal by using automatic enzyme-labeled catalytic substrate and application thereof 苏州科技大学 2023-06-02 CN claimed
CN-116200464-A Method and kit for detecting nucleic acid based on electrochemical signal substrate amplification 苏州科技大学 2023-06-02 CN claimed
CN-116200253-A DNA sequencing micro-fluidic biochip and method for automatically amplifying signals by rolling circle amplification of nucleic acid and double amplification of enzyme-labeled catalytic substrate 苏州科技大学 2023-06-02 CN claimed
CN-116203228-A Ultrasensitive microfluidic sandwich enzyme-linked immunosorbent assay detection platform based on DNA signal amplification and electrochemical detection and application 苏州科技大学 2023-06-02 CN claimed
CN-216786121-U DNA sequencing micro-fluidic biochip for automatically amplifying signals of nucleic acid rolling circle amplification and enzyme-labeled catalytic substrate double amplification 苏州科技大学 2022-06-21 CN claimed
CN-110501318-B Fluorescence method for detecting alkaline phosphatase activity 中国科学院长春应用化学研究所 2020-11-13 CN claimed
US-20160115194-A1 PROTEIN PURIFICATION PROCESS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2016-04-28 US claimed
EP-3004135-A1 PROTEIN PURIFICATION PROCESS Agency For Science, Technology And Research (SG) 2016-04-13 EP claimed
WO-2014196926-A1 PROTEIN PURIFICATION PROCESS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-12-11 WO claimed
US-20140329254-A1 BIOSENSOR USING REDOX CYCLING PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2014-11-06 US claimed
US-20100243479-A1 SENSOR FOR DETECTING STEM CELL DIFFERENTIATION BASED ON ELECTROCHEMICAL METHODS Industry-University Cooperation Foundation Sogang University (KR) 2010-09-30 US claimed
US-5981203-A NON-SEPARATION ASSAY BY USING REACTION VESSEL DIVIDED BY MICROPOROUS SUPPORT COATED WITH ANTIBODIES CAPTURING SAMPLE/ LABELED ANTIBODY COMPLEX AND ELECTROCONDUCTIVE METAL LAYER WHICH ACTS AS ELECTRODE AND MEASURES REACTED ENZYME SUBSTRATE THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1999-11-09 US claimed
US-5830680-A ELECTROCONDUCTIVE METAL AND CAPTURING ANTIBODY ON MICROPOROUSMEMBRANES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1998-11-03 US claimed
WO-1995029395-A1 UNITARY SANDWICH ENZYME IMMUNOASSAY CASSETTE, DEVICE AND METHOD OF USE THE REGENTS OF UNIVERSITY OF MICHIGAN (US) 1995-11-02 WO claimed
US-5124253-A For generating electroactive compound from corresponding phosphite ester MEDISENSE, INC. (US) 1992-06-23 US claimed
EP-2961782-B2 POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME HONEYWELL INT INC (US) 2025-11-26 EP disclosed
US-20250075048-A1 POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME HONEYWELL INTERNATIONAL INC. (US) 2025-03-06 US disclosed
US-5149629-A Biologically active entities immobilized on electrode, tagged with an enzyme providing signal; multiplexer combined with potentiostat; rapid analysis for hospitals, clinics RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) 1992-09-22 US disclosed
EP-0424586-A2 Method and apparatus for electrochemical immunoassay IMMUNOSENS SPA (IT) 1991-05-02 EP disclosed
EP-0286084-A2 A device for the rapid qualitative or quantitative assay of entities having a biological activity RAMOT UNIVERSITY, AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) 1988-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160115194-A1 PROTEIN PURIFICATION PROCESS HIRA, HGFAC, MAX ALDH1A1 4017/4885ADRA2B 4345/4885PTGS1 3046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.