Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699762 | 0.91 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL28347236 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL28790810 | 0.83 | ALDH1A1 (0.43) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL569537 | 0.78 | INPPL1 (0.57) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL30118861 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL10321089 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL28687913 | 0.77 | INPPL1 (0.55) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL28665448 | 0.77 | INPPL1 (0.55) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL28678394 | 0.77 | INPPL1 (0.55) | ALDH1A1ADRA2BPTGS1TDP1LMNA | |
| SCHEMBL5334638 | 0.76 | SRC (0.44) | ALDH1A1ADRA2BPTGS1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142626-A1 | CROSS-LINKING REAGENTS FOR HEMOGLOBIN AND HEMOGLOBIN PRODUCTS CROSS-LINKED THEREWITH | KLUGER RONALD | 2007-06-21 | — | — | US | claimed |
| WO-2007065265-A1 | CROSS-LINKING REAGENTS FOR HEMOGLOBIN AND HEMOGLOBIN PRODUCTS CROSS-LINKED THEREWITH | KLUGER RONALD (CA) | 2007-06-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142626-A1 | CROSS-LINKING REAGENTS FOR HEMOGLOBIN AND HEMOGLOBIN PRODUCTS CROSS-LINKED THEREWITH | HBG2, HBB, HBG1 | ALDH1A1 1740/4885ADRA2B 3893/4885PTGS1 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.