Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16999571 | 1.00 | CHEK1 (0.51) | CHEK1USP30GAAHSD17B10CTSL | |
| SCHEMBL18261141 | 1.00 | CHEK1 (0.51) | CHEK1USP30GAAHSD17B10CTSL | |
| SCHEMBL16999853 | 0.90 | KCNQ2 (0.56) | USP30GAACTSLCTSSCTSK | |
| SCHEMBL24862942 | 0.90 | USP30 (0.50) | CHEK1USP30GAAHSD17B10PLA2G1B | |
| SCHEMBL16993962 | 0.88 | USP30 (0.45) | USP30CTSLCTSSCTSKKMT2A | |
| SCHEMBL16999355 | 0.87 | ALDH1A1 (0.58) | PLA2G1BSMN1; SMN2ATG4BKMT2AALDH1A1 | |
| SCHEMBL16994050 | 0.87 | HSD17B10 (0.64) | USP30GAAHSD17B10CTSLCTSS | |
| SCHEMBL16993884 | 0.87 | USP30 (0.48) | USP30GAAHSD17B10CTSLCTSS | |
| SCHEMBL16999804 | 0.87 | L3MBTL1 (0.52) | CHEK1GAAHSD17B10CTSLCTSS | |
| SCHEMBL16999499 | 0.87 | ALDH1A1 (0.53) | CHEK1GAAHSD17B10CTSLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120320-A1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-13 | — | — | WO | disclosed |