Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16964168 | 0.93 | MAPT (0.51) | MAPTHPGDALDH1A1KMT2APIK3CD | |
| SCHEMBL16964049 | 0.89 | MAPT (0.54) | MAPTHPGDALDH1A1KMT2APIK3CD | |
| SCHEMBL16964226 | 0.88 | ALDH1A1 (0.57) | MAPTHPGDALDH1A1KMT2APIK3CD | |
| SCHEMBL17000511 | 0.87 | MAPT (0.52) | MAPTHPGDALDH1A1KMT2APIK3CD | |
| SCHEMBL16964173 | 0.83 | MAPT (0.51) | MAPTHPGDALDH1A1KMT2APIK3CD | |
| SCHEMBL16964202 | 0.83 | MAPT (0.53) | MAPTHPGDALDH1A1KMT2APIK3CD | |
| SCHEMBL16963677 | 0.82 | CDK5 (0.41) | MAPTALDH1A1KMT2APIK3CDPIK3CB | |
| SCHEMBL19976448 | 0.82 | ADRB3 (0.42) | MAPTLMNANPSR1HTTTSHR | |
| SCHEMBL16991074 | 0.81 | MAPT (0.54) | MAPTHPGDALDH1A1KMT2ALMNA | |
| SCHEMBL19976509 | 0.81 | KDM1A (0.39) | MAPTKMT2APIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |
| EP-2900638-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | UNIVERSITÉ DE DROIT ET DE LA SANTÉ DE LILLE 2 (FR) | 2017-01-04 | — | — | EP | disclosed |
| US-20150225388-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225388-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | C5, ALK, TYR | MAPT 2146/4885HPGD 3110/4885ALDH1A1 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.