Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16964049 | 0.90 | MAPT (0.54) | MAPTALDH1A1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL17000548 | 0.87 | MAPT (0.56) | MAPTALDH1A1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16964168 | 0.82 | MAPT (0.51) | MAPTALDH1A1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16991074 | 0.81 | MAPT (0.54) | MAPTALDH1A1HPGDRAB9AHTT | |
| SCHEMBL19976447 | 0.80 | MAPT (0.47) | MAPTALDH1A1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16964226 | 0.79 | ALDH1A1 (0.57) | MAPTALDH1A1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16964173 | 0.78 | MAPT (0.51) | MAPTALDH1A1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16964202 | 0.77 | MAPT (0.53) | MAPTALDH1A1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL19976508 | 0.76 | MAPT (0.64) | MAPTALDH1A1HPGDRAB9AHTT | |
| SCHEMBL16963677 | 0.72 | CDK5 (0.41) | MAPTALDH1A1PIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150225388-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225388-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | C5, ALK, TYR | MAPT 2146/4885ALDH1A1 2650/4885PIK3CD 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.