Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MYB | P10242 | 10/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17001453 | 0.89 | KDM4E (0.42) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL18268186 | 0.80 | KDM4E (0.48) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL18268188 | 0.80 | KDM4E (0.48) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL18268202 | 0.80 | KDM4E (0.48) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL17001456 | 0.77 | LMNA (0.44) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL19669613 | 0.74 | KDM4E (0.41) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL19669616 | 0.74 | KDM4E (0.41) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL19669617 | 0.74 | KDM4E (0.41) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL18268184 | 0.74 | CA2 (0.42) | MAPTKDM4EMEN1ALDH1A1BLM | |
| SCHEMBL18270509 | 0.73 | MEN1 (0.41) | MAPTKDM4EMEN1ALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120059-A1 | INHIBITORS OF PAXILLIN FUNCTION AND RELATED COMPOSITIONS AND METHODS | YATES CHARLES RYAN (US) | 2015-08-13 | — | — | WO | disclosed |