Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18382073 | 1.00 | RAB9A (0.36) | RAB9ADPP7NPC1SMN1; SMN2POLB | |
| SCHEMBL20310809 | 0.86 | L3MBTL3 (0.37) | RAB9ADPP7NPC1SMN1; SMN2POLB | |
| SCHEMBL17001687 | 0.86 | L3MBTL3 (0.37) | RAB9ADPP7NPC1SMN1; SMN2POLB | |
| SCHEMBL17001672 | 0.85 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL17001686 | 0.84 | RAB9A (0.36) | RAB9ADPP7NPC1SMN1; SMN2POLB | |
| SCHEMBL17001666 | 0.84 | BCHE (0.38) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL18382128 | 0.82 | HCRTR2 (0.39) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL17001685 | 0.79 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL17001676 | 0.79 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL17001662 | 0.79 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015118342-A1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS. | HEPTARES THERAPEUTICS LIMITED (GB) | 2015-08-13 | — | — | WO | disclosed |