SCHEMBL1700253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2483201	1.00	MAPT (0.50)	MAPTGAAALDH1A1LMNAHTT
	SCHEMBL1700252	1.00	MAPT (0.50)	MAPTGAAALDH1A1LMNAHTT
	SCHEMBL31344646	0.94	MAPT (0.52)	MAPTGAAALDH1A1LMNAHTT
	SCHEMBL1700051	0.94	MAPT (0.52)	MAPTGAAALDH1A1LMNAHTT
	SCHEMBL1700079	0.92	MAPT (0.48)	MAPTGAAALDH1A1LMNAHTT
	SCHEMBL1957904	0.91	MAPT (0.49)	MAPTGAAALDH1A1LMNAHTT
	SCHEMBL1700242	0.89	MAPT (0.47)	MAPTGAAALDH1A1LMNAHTT
	SCHEMBL28539193	0.85	USP30 (0.52)	MAPTALDH1A1LMNAHTTPOLB
	SCHEMBL28539191	0.85	USP30 (0.52)	MAPTALDH1A1LMNAHTTPOLB
	SCHEMBL16513098	0.85	LMNA (0.47)	MAPTALDH1A1LMNAHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.