Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910137 | 1.00 | USP30 (0.52) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL28539193 | 1.00 | USP30 (0.52) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL29791919 | 0.94 | ALDH1A1 (0.52) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL10059190 | 0.94 | ALDH1A1 (0.52) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL14247649 | 0.92 | USP30 (0.52) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL15342506 | 0.92 | USP30 (0.52) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL15342513 | 0.92 | USP30 (0.52) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL2252021 | 0.92 | USP30 (0.45) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL16513098 | 0.88 | LMNA (0.47) | USP30MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL2253805 | 0.87 | MAPK1 (0.46) | USP30MAPK1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043458-A1 | EP300/CBP INHIBITOR | Hinova Pharmaceuticals Inc. (CN) | 2022-08-17 | — | — | EP | disclosed |
| CN-112574189-A | EP300/CBP inhibitor | 海创药业股份有限公司 | 2021-03-30 | — | — | CN | disclosed |