Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14916922 | 0.75 | S1PR1 (0.42) | ALDH1A1KMT2AMEN1HTTGAA | |
| Hydrochloric Acid SCHEMBL14916431 | 0.74 | S1PR1 (0.42) | ALDH1A1KMT2AMEN1HTTGAA | |
| SCHEMBL321038 | 0.74 | KDM4E (0.42) | ALDH1A1KMT2AMEN1HTTGAA | |
| SCHEMBL12505747 | 0.72 | POLB (0.42) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL321292 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1GAAKDM4E | |
| SCHEMBL321434 | 0.65 | L3MBTL1 (0.55) | ALDH1A1KMT2AMEN1HTTGAA | |
| SCHEMBL320647 | 0.65 | ALDH1A1 (0.41) | ALDH1A1KMT2AHTTGAAMAPT | |
| SCHEMBL320396 | 0.63 | ALDH1A1 (0.43) | ALDH1A1HTTGAAMAPTKDM4E | |
| SCHEMBL28811758 | 0.63 | MAPT (0.39) | ALDH1A1KMT2AMEN1HTTGAA | |
| SCHEMBL320837 | 0.63 | MAPT (0.41) | ALDH1A1KMT2AMEN1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590975-B1 | INDOLIZINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2015-08-19 | — | — | EP | claimed |