Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004377 | 0.91 | MET (0.44) | METMAOBHCRTR1ALDH1A1RAB9A | |
| SCHEMBL17004383 | 0.87 | MET (0.49) | METALDH1A1RAB9AKMT2AF10 | |
| SCHEMBL12922889 | 0.84 | MAOB (0.50) | MAOBNPSR1HCRTR1ALDH1A1HPGD | |
| SCHEMBL980169 | 0.84 | MAOB (0.45) | METMAOBNPSR1HCRTR1ALDH1A1 | |
| SCHEMBL12922936 | 0.82 | MET (0.61) | MET | |
| SCHEMBL14609906 | 0.82 | MET (0.60) | METMGLL | |
| SCHEMBL980870 | 0.81 | MAOB (0.53) | MAOBALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL981591 | 0.80 | ALDH1A1 (0.57) | MAOBALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5046607 | 0.79 | MET (0.68) | METALDH1A1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5050480 | 0.78 | MET (0.67) | METALDH1A1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917248-B1 | 1-ACYLDIHYDROPYRAZOL DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-08-19 | — | — | EP | claimed |