SCHEMBL1700516

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1700457	0.90	LMNA (0.43)	LMNACYP19A1MAPTNPSR1MAPK1
	SCHEMBL29855648	0.90	LMNA (0.43)	LMNACYP19A1MAPTNPSR1MAPK1
	SCHEMBL1700700	0.85	CA2 (0.44)	LMNACYP19A1MAPTNPSR1MAPK1
	SCHEMBL1700699	0.85	CA2 (0.44)	LMNACYP19A1MAPTNPSR1MAPK1
	SCHEMBL1700698	0.85	CA2 (0.44)	LMNACYP19A1MAPTNPSR1MAPK1
	SCHEMBL1700056	0.81	LMNA (0.51)	LMNAMAPTBRD4CA1CA2
	SCHEMBL2698145	0.80	LMNA (0.42)	LMNACYP19A1MAPTNPSR1MAPK1
	SCHEMBL22581459	0.79	LMNA (0.43)	LMNAMAPTNPSR1MAPK1PKM
	SCHEMBL30777650	0.79	LMNA (0.43)	LMNAMAPTNPSR1MAPK1PKM
	SCHEMBL1699921	0.78	BRD4 (0.45)	LMNACYP19A1MAPTNPSR1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.