SCHEMBL17006293

SCHEMBL17006293

CCCCc1cc(C2(c3ccc(O)c(CCCC)c3)c3ccccc3-c3ccccc32)ccc1O.O=C(O)c1ccc2c(c1)C(=O)OC2=O.O=C(O)c1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
TTR P02766 2/20 0.36
PDK2 Q15119 2/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA4 P22748 2/20 0.35
CA7 P43166 2/20 0.35
PTPRC P08575 2/20 0.35
POLB P06746 2/20 0.34
KMT2A Q03164 1/20 0.34
RXRA P19793 1/20 0.34
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33
CNR2 P34972 1/20 0.33
RARB P10826 1/20 0.33
LTB4R Q15722 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17006301 0.94 ESR1 (0.42) ESR1ESR2GAAPKMTTR
SCHEMBL17006298 0.91 ESR1 (0.44) ESR1ESR2GAAPKMTTR
SCHEMBL17006288 0.83 PDK2 (0.38) GAATTRPDK2CA12CA1
SCHEMBL17006300 0.83 ESR1 (0.62) ESR1ESR2GAAPKMTTR
SCHEMBL29842359 0.82 ESR1 (0.57) ESR1ESR2PDK2POLBKMT2A
SCHEMBL383048 0.82 ESR1 (0.57) ESR1ESR2PDK2POLBKMT2A
SCHEMBL17006291 0.81 ESR1 (0.43) ESR1ESR2GAAPKMTTR
SCHEMBL17006289 0.80 ESR1 (0.43) ESR1ESR2GAAPKMTTR
SCHEMBL15754326 0.79 CA12 (0.46) ESR1ESR2GAAPKMTTR
SCHEMBL5487840 0.79 ESR1 (0.56) ESR1ESR2POLBKMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150232665-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-08-20 US disclosed