Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572279 | 0.99 | ESR1 (0.55) | ESR1ESR2TYRMEN1MAPT | |
| SCHEMBL383048 | 0.96 | ESR1 (0.57) | ESR1ESR2TYRMEN1MAPT | |
| SCHEMBL29842359 | 0.96 | ESR1 (0.57) | ESR1ESR2TYRMEN1MAPT | |
| SCHEMBL383400 | 0.90 | ESR1 (0.60) | ESR1ESR2MEN1MAPTKMT2A | |
| SCHEMBL29842572 | 0.90 | ESR1 (0.60) | ESR1ESR2MEN1MAPTKMT2A | |
| SCHEMBL19334604 | 0.86 | ESR1 (0.56) | ESR1ESR2MEN1MAPTKMT2A | |
| SCHEMBL19843860 | 0.85 | ESR1 (0.55) | ESR1ESR2MEN1MAPTKMT2A | |
| SCHEMBL29587240 | 0.84 | ESR1 (0.64) | ESR1ESR2MEN1MAPTKMT2A | |
| SCHEMBL383087 | 0.84 | ESR1 (0.64) | ESR1ESR2MEN1MAPTKMT2A | |
| SCHEMBL14129175 | 0.82 | ESR1 (0.43) | ESR1ESR2TYRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070255075-A1 | Aromatic Diamine And Method For Manufacturing Same | JFE CHEMICAL CORPORATION (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1803705-A1 | AROMATIC DIAMINE AND PROCESS FOR PRODUCING THE SAME | JFE Chemical Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070255075-A1 | Aromatic Diamine And Method For Manufacturing Same | AOC1, DDC, PADI1 | ESR1 1381/4885ESR2 2044/4885TYR 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.