Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18892313 | 1.00 | CTSK (0.45) | CTSKGPR119SLC6A9 | |
| SCHEMBL18892468 | 0.91 | CTSK (0.44) | CTSKGPR119SLC6A9 | |
| SCHEMBL17008289 | 0.89 | CTSK (0.39) | CTSKGPR119 | |
| SCHEMBL17008214 | 0.87 | CTSK (0.52) | CTSKGPR119SLC6A9 | |
| SCHEMBL17008212 | 0.87 | CTSK (0.45) | CTSKGPR119SLC6A9 | |
| SCHEMBL18279701 | 0.87 | CTSK (0.45) | CTSKGPR119SLC6A9 | |
| SCHEMBL18279702 | 0.87 | CTSK (0.52) | CTSKGPR119SLC6A9 | |
| SCHEMBL17008388 | 0.86 | CTSK (0.63) | CTSK | |
| SCHEMBL18279763 | 0.86 | CTSK (0.63) | CTSK | |
| SCHEMBL17008305 | 0.86 | CTSK (0.47) | CTSKSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120580-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-08-20 | — | — | WO | disclosed |