Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | RECQL | P46063 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | MTOR | P42345 | 5/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741777 | 0.86 | TUBB4A (0.53) | KDM4ETDP1MAPTRECQLHSD17B10 | |
| SCHEMBL2859477 | 0.80 | TDP1 (0.53) | KDM4ETDP1MAPTRECQLHSD17B10 | |
| SCHEMBL10582745 | 0.79 | TDP1 (0.57) | KDM4ETDP1MAPTRECQLHSD17B10 | |
| SCHEMBL18479371 | 0.77 | KDM4E (0.61) | KDM4ETDP1MAPTRECQLHSD17B10 | |
| SCHEMBL20821160 | 0.77 | KDM4E (0.61) | KDM4ETDP1MAPTRECQLHSD17B10 | |
| SCHEMBL8741805 | 0.77 | TSHR (0.46) | ALOX15TSHRNFKB1BLMALDH1A1 | |
| SCHEMBL3937368 | 0.77 | TDP1 (0.59) | KDM4ETDP1MAPTRECQLHSD17B10 | |
| SCHEMBL29362968 | 0.77 | TRPA1 (0.67) | KDM4ETDP1MAPTRECQLHSD17B10 | |
| SCHEMBL172232 | 0.77 | TRPA1 (0.67) | KDM4ETDP1MAPTRECQLHSD17B10 | |
| SCHEMBL29525823 | 0.77 | TDP1 (0.65) | KDM4ETDP1MAPTRECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748767-A4 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS INC (US) | 2008-12-24 | — | — | EP | claimed |
| EP-1748767-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | Unigen Pharmaceuticals, Inc. (US) | 2007-02-07 | — | — | EP | claimed |
| WO-2005117849-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | claimed |
| EP-2584897-A1 | RESVERATROL-CONTAINING COMPOSITIONS AND METHODS OF USE | Resveratrol Partners, Llc (US) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012006065-A1 | RESVERATROL-CONTAINING COMPOSITIONS AND METHODS OF USE | RESVERATROL PARTNERS, LLC (US) | 2012-01-12 | — | — | WO | disclosed |
| EP-0297733-A2 | Pharmaceutical compositions comprising catecholic butanes | BLOCK DRUG COMPANY, INC. (US) | 1989-01-04 | — | — | EP | disclosed |