Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25716511 | 0.63 | DRD2 (0.47) | KDM4E | |
| SCHEMBL15202744 | 0.61 | CYP19A1 (0.43) | KDM4E | |
| SCHEMBL17001810 | 0.61 | HTR1D (0.41) | HTR1DHTR1BHTR1F | |
| SCHEMBL27975805 | 0.60 | RET (0.42) | — | |
| SCHEMBL1662575 | 0.59 | — | — | |
| SCHEMBL12049586 | 0.59 | PDE9A (0.32) | — | |
| SCHEMBL23580267 | 0.58 | HSP90AA1 (0.38) | HRH4KDM4E | |
| Hydrochloric Acid SCHEMBL10696855 | 0.57 | — | — | |
| SCHEMBL14003846 | 0.56 | CHRNB2 (0.33) | HRH4 | |
| SCHEMBL2741394 | 0.56 | CHRNB2 (0.33) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105207-A1 | GPR142 AGONIST COMPOUNDS | Eli Lilly and Company (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015120768-A1 | GPR142 AGONIST COMPOUNDS | ELI LILLY AND COMPANY (US) | 2015-08-20 | — | — | WO | disclosed |