Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10141583 | 0.72 | DAO (0.44) | DAORAB9ATP53USP2SMN1; SMN2 | |
| SCHEMBL27992675 | 0.68 | DAO (0.58) | DAOTP53LMNAALDH1A1 | |
| SCHEMBL5447840 | 0.67 | — | — | |
| SCHEMBL29256493 | 0.67 | DAO (0.43) | DAORAB9ATP53USP2SMN1; SMN2 | |
| SCHEMBL5801700 | 0.66 | ERN1 (0.38) | ALDH1A1 | |
| SCHEMBL16212189 | 0.66 | MAPK1 (0.45) | RAB9ATP53SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL256012 | 0.65 | — | — | |
| SCHEMBL4633358 | 0.64 | CYP3A4 (0.39) | RAB9ATP53SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL17428955 | 0.64 | LMNA (0.45) | DAORAB9ATP53SMN1; SMN2MAPT | |
| Ammonia Solution, Strong SCHEMBL2216424 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585459-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | Chiesi Farmaceutici S.p.A. (IT) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011161018-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-29 | — | — | WO | disclosed |