Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960285 | 0.79 | ACP3 (0.43) | ALDH1A1TSHR | |
| SCHEMBL21597319 | 0.76 | CYP2A6 (0.42) | ALDH1A1 | |
| SCHEMBL2468299 | 0.76 | CYP2A6 (0.42) | ALDH1A1 | |
| SCHEMBL27961318 | 0.76 | ERN1 (0.34) | ERN1 | |
| SCHEMBL22833975 | 0.74 | ERN1 (0.32) | ERN1ALDH1A1 | |
| SCHEMBL3410995 | 0.74 | ERN1 (0.32) | ERN1ALDH1A1 | |
| SCHEMBL1100811 | 0.73 | ERN1 (0.39) | ERN1ALDH1A1TSHRTPMT | |
| SCHEMBL15687876 | 0.71 | BACE1 (0.38) | TSHR | |
| SCHEMBL21724409 | 0.71 | TSHR (0.38) | ERN1TSHRTPMT | |
| SCHEMBL4709591 | 0.71 | CES2 (0.38) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322705-A1 | 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS | F2G Limited (GB) | 2018-05-23 | — | — | EP | disclosed |
| WO-2017009651-A1 | 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS | F2G LIMITED (GB) | 2017-01-19 | — | — | WO | disclosed |
| EP-2822928-A1 | SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2015-01-14 | — | — | EP | disclosed |
| WO-2013131408-A1 | SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS | DR.REDDY'S LABORATORIES LTD. (IN) | 2013-09-12 | — | — | WO | disclosed |
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |