Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18959563 | 0.85 | GPR119 (0.39) | — | |
| SCHEMBL18964045 | 0.85 | GPR119 (0.39) | — | |
| SCHEMBL17010140 | 0.72 | CTSK (0.41) | LMNA | |
| SCHEMBL17010038 | 0.71 | ACE (0.33) | — | |
| SCHEMBL6752548 | 0.68 | IDO1 (0.38) | LMNA | |
| SCHEMBL6750129 | 0.68 | IDO1 (0.38) | LMNA | |
| SCHEMBL15270881 | 0.68 | SPHK1 (0.31) | — | |
| SCHEMBL1067660 | 0.68 | SPHK1 (0.31) | — | |
| SCHEMBL1067656 | 0.68 | SPHK1 (0.31) | — | |
| SCHEMBL3614629 | 0.68 | SPHK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3104707-B1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE MEDICINE INC (US) | 2020-07-15 | — | — | EP | disclosed |
| US-10294233-B2 | Treatment of H. pylori infections using MTAN inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2019-05-21 | — | — | US | disclosed |
| US-20190016730-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2019-01-17 | — | — | US | disclosed |
| US-10118928-B2 | Treatment of H. pylori infections using MTAN inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2018-11-06 | — | — | US | disclosed |
| US-20170166571-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-06-15 | — | — | US | disclosed |
| EP-3104707-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | Albert Einstein College of Medicine, Inc. (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015123101-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10118928-B2 | Treatment of H. pylori infections using MTAN inhibitors | MTAP, UNG, PNP | LMNA 2964/4885 |
| US-20170166571-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | MTAP, PNP, UNG | LMNA 3250/4885 |
| US-10294233-B2 | Treatment of H. pylori infections using MTAN inhibitors | MTAP, PNP, UNG | LMNA 3250/4885 |
| US-20190016730-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | MTAP, PNP, UNG | LMNA 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.