Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.40 |
| ▸ | CHRNG | P07510 | 4/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.40 |
| ▸ | CHRND | Q07001 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765845 | 0.80 | FDPS (0.37) | MAOBALDH1A1GAAACHENPC1 | |
| SCHEMBL15615636 | 0.79 | MAPT (0.47) | ALDH1A1GAASMN1; SMN2KMT2A | |
| SCHEMBL27992779 | 0.78 | SLC6A3 (0.42) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27647452 | 0.77 | MAOB (0.46) | MAOBSLC6A2CHRNB4CHRNA3SLC6A3 | |
| SCHEMBL10939615 | 0.75 | DPP7 (0.45) | MAOBSLC6A2CHRNB4CHRNA3SLC6A3 | |
| SCHEMBL12462690 | 0.75 | MAOB (0.44) | MAOBSLC6A2CHRNB4CHRNA3SLC6A3 | |
| SCHEMBL12937998 | 0.75 | MAOB (0.44) | MAOBSLC6A2CHRNB4CHRNA3SLC6A3 | |
| Hydrochloric Acid SCHEMBL11682964 | 0.75 | MAOB (0.44) | MAOBSLC6A2CHRNB4CHRNA3SLC6A3 | |
| SCHEMBL4938808 | 0.75 | DPP7 (0.45) | MAOBSLC6A2CHRNB4CHRNA3SLC6A3 | |
| SCHEMBL14850491 | 0.75 | MAOB (0.44) | MAOBSLC6A2CHRNB4CHRNA3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105219-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | Incyte Corporation (US) | 2016-12-21 | — | — | EP | claimed |
| WO-2015123408-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2015-08-20 | — | — | WO | claimed |