SCHEMBL1701190

SCHEMBL1701190

Oc1c(Cl)cnc(Cl)c1Cl.Oc1c(Cl)cnc(Cl)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.40
HPGD P15428 5/20 0.40
TSHR P16473 5/20 0.40
MAPK1 P28482 2/20 0.40
PDXK O00764 1/20 0.39
CASP1 P29466 1/20 0.38
CYP3A4 P08684 4/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 3/20 0.32
LMNA P02545 3/20 0.32
MAPT P10636 3/20 0.32
KMT2A Q03164 3/20 0.32
HSP90AA1 P07900 2/20 0.32
HTR1A P08908 2/20 0.32
ALOX15 P16050 2/20 0.32
ALOX12 P18054 2/20 0.32
SLC6A2 P23975 2/20 0.32
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135431 1.00 HSD17B10 (0.40) HSD17B10HPGDTSHRMAPK1PDXK
SCHEMBL172310 0.79 HSD17B10 (0.40) HSD17B10HPGDTSHRMAPK1PDXK
SCHEMBL20862093 0.75 CYP3A4 (0.37) PDXKCYP3A4ALDH1A1ALOX15CHRM1
SCHEMBL9880643 0.75 PLAU (0.37) PDXKPLAU
SCHEMBL30012993 0.75 CYP3A4 (0.37) PDXKCYP3A4ALDH1A1ALOX15CHRM1
SCHEMBL29462909 0.75 CYP3A4 (0.35) CYP3A4SMN1; SMN2KDM4EPLAUPOLB
SCHEMBL6651470 0.75 CYP3A4 (0.35) CYP3A4SMN1; SMN2KDM4EPLAUPOLB
SCHEMBL31236207 0.72 CYP3A4 (0.33) CYP3A4
SCHEMBL28984987 0.70 MEN1 (0.44) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL31071678 0.70 MEN1 (0.44) HSD17B10HPGDTSHRMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130210630-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (DE) 2013-08-15 US disclosed
WO-2012003441-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (US) 2012-01-05 WO disclosed
US-7019046-B2 Aqueous suspension agent for water insoluble compounds ISP INVESTMENTS INC. (US) 2006-03-28 US disclosed
US-20060039944-A1 Solid polymeric dispersant composition for water-insoluble actives ISP INVESTMENTS INC. 2006-02-23 US disclosed
US-20040024099-A1 Aqueous suspension agent for water insoluble compounds ISP INVESTMENTS INC. 2004-02-05 US disclosed
EP-0668757-B1 COMPOSITIONS OF INSOLUBLE FILM-FORMING POLYMERS AND USES THEREFOR ISP INVESTMENTS INC (US) 2003-12-10 EP disclosed
US-6303131-B1 CAN BE USED AS A COATING FOR SUBSTRATES, SUCH AS, WOOD, METAL, GLASS, ALSO ACTIVE INGREDIENT, E.G., FUNGICIDES, PRESERVATIVES, INSECTICIDES, INSECT REPELLENTS, PHEROMONES, RADIATION ABSORBENTS, DYES, CAN BE INCLUDED IN FORMULATION ISP INVESTMENTS INC. 2001-10-16 US disclosed
EP-0574492-B1 STABILIZATION OF MICROEMULSIONS USING HYDROPHOBIC ACID BUFFERS ISP INVESTMENTS INC (US) 1999-05-12 EP disclosed
US-5766615-A MIXTURE CONTAINING LONG-CHAIN ALKYLPYRROLIDONE, ANIONIC SURFACTANT, GRAFT POLYMER OF N-VINYLPYRROLIDONE AND AN ALPHA-OLEFIN AND AN AGRICULTURALLY ACTIVE COMPOUND ISP INVESTMENTS INC. (US) 1998-06-16 US disclosed
WO-1998006780-A1 STABILIZER ADDITIVE FOR AGCHEMICAL TANK MIX ISP INVESTMENTS INC. (US) 1998-02-19 WO disclosed
US-5389297-A An alkypyrrolidone; an anionic surfactant; water-soluble, high melting organic compound having a dissociable proton which can complex with the pyrrolidone ISP INVESTMENTS INC. (US) 1995-02-14 US disclosed
US-5354726-A Hydrophilic and hydrophobic solvents prevent precipitation on extended storage ISP INVESTMENTS INC. (US) 1994-10-11 US disclosed
US-5300529-A Stable, clear, efficacious aqueous microemulsion compositions containing a high loading of a water-insoluble, agriculturally active chemical ISP INVESTMENTS INC. (US) 1994-04-05 US disclosed
US-5283229-A A concentrate emulsions comprising an active materials, a surfactant and an amide solvent mixtures to dissolve, dispersing the water insoluble active materials; stability ISP INVESTMENTS INC. (US) 1994-02-01 US disclosed
US-5250499-A Delivery system for agricultural chemicals ISP INVESTMENTS INC. (US) 1993-10-05 US disclosed
US-5176736-A Emulsifiable herbicide concentrate ISP INVESTMENTS INC. (US) 1993-01-05 US disclosed
US-5160528-A Stable emulsifiable herbicide concentrates ISP INVESTMENTS INC. (US) 1992-11-03 US disclosed
US-5156666-A Emulsifiable concentrate comprising a pesticide, a surfactant, a hydrophobic solvent and a hydrophilic solvent; storage stability ISP INVESTMENTS INC. (US) 1992-10-20 US disclosed
EP-0505378-A1 DELIVERY SYSTEM FOR AGRICULTURAL CHEMICALS ISP INVESTMENTS INC. (US) 1992-09-30 EP disclosed
US-5071463-A Stable, emulsifiable concentrate of an herbicide and pyrrolido ne derivative; dispersibility ISP INVESTMENTS INC. (US) 1991-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210630-A1 SELF-EMULSIFYING OIL PHOSPHO1, SQLE, ALOX15 HSD17B10 549/4885HPGD 1874/4885TSHR 4755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.