Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PDXK | O00764 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15495385 | 0.81 | PDXK (0.41) | PDXKTNF | |
| SCHEMBL18326515 | 0.81 | PLAU (0.37) | PLAUDAOTNF | |
| SCHEMBL6664399 | 0.75 | PLAU (0.44) | PLAUDAO | |
| SCHEMBL1701190 | 0.75 | HSD17B10 (0.40) | PLAUPDXK | |
| SCHEMBL135431 | 0.75 | HSD17B10 (0.40) | PLAUPDXK | |
| SCHEMBL26287526 | 0.73 | KDM4E (0.42) | PLAUPDXKDAOTNF | |
| SCHEMBL1961170 | 0.71 | PLAU (0.33) | PLAUPDXK | |
| SCHEMBL16972785 | 0.70 | PLAU (0.48) | PLAUDAO | |
| SCHEMBL23088450 | 0.70 | ALDH1A1 (0.44) | — | |
| SCHEMBL28793349 | 0.68 | PLAU (0.42) | PLAUDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643312-B1 | MICROBICIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| US-8748431-B2 | Microbicidal heterocycles | SYNGENTA PARTICIPATIONS AG (CH) | 2014-06-10 | — | — | US | disclosed |
| US-8748431-B2 | Microbicidal heterocycles | SYNGENTA PARTICIPATIONS AG (CH) | 2014-06-10 | — | — | US | disclosed |
| WO-2012069633-A1 | MICROBICIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |