Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967507 | 0.81 | KCNN4 (0.49) | KCNN4KIF11KCNA3CYP1A2CYP2D6 | |
| SCHEMBL4855348 | 0.80 | KCNN4 (0.43) | KCNN4CYP1A2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL27824023 | 0.79 | KCNN4 (0.53) | KCNN4KIF11KCNA3CYP1A2CYP2D6 | |
| SCHEMBL16416723 | 0.74 | KCNN4 (0.45) | KCNN4KIF11KCNA3CYP1A2CYP2D6 | |
| SCHEMBL27183395 | 0.73 | KCNN4 (0.57) | KCNN4KIF11KCNA3CYP1A2CYP2D6 | |
| SCHEMBL7901027 | 0.72 | KCNN4 (0.42) | KCNN4KIF11KCNA3CYP1A2CYP2D6 | |
| SCHEMBL2406097 | 0.71 | KCNN4 (0.46) | KCNN4KIF11KCNA3CYP1A2CYP2D6 | |
| SCHEMBL27459558 | 0.71 | KCNN4 (0.72) | KCNN4KIF11KCNA3CYP1A2CYP2D6 | |
| SCHEMBL27558142 | 0.71 | KCNN4 (0.64) | KCNN4KIF11KCNA3CYP1A2CYP2D6 | |
| SCHEMBL1001586 | 0.70 | KCNN4 (1.00) | KCNN4KIF11KCNA3CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566883-A1 | NOVEL PROCESS FOR THE PREPARATION OF LEUPROLIDE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Mylan Laboratories, Limited (IN) | 2013-03-13 | — | — | EP | claimed |
| US-20130060004-A1 | Novel Process For The Preparation Of Leuprolide And Its Pharmaceutically Acceptable Salts Thereof | MYLAN LABORATORIES LIMITED (IN) | 2013-03-07 | — | — | US | claimed |
| WO-2011148384-A1 | NOVEL PROCESS FOR THE PREPARATION OF LEUPROLIDE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | MATRIX LABORATORIES LTD (IN) | 2011-12-01 | — | — | WO | claimed |
| EP-2566883-A1 | NOVEL PROCESS FOR THE PREPARATION OF LEUPROLIDE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Mylan Laboratories, Limited (IN) | 2013-03-13 | — | — | EP | disclosed |
| US-20130060004-A1 | Novel Process For The Preparation Of Leuprolide And Its Pharmaceutically Acceptable Salts Thereof | MYLAN LABORATORIES LIMITED (IN) | 2013-03-07 | — | — | US | disclosed |
| WO-2011148384-A1 | NOVEL PROCESS FOR THE PREPARATION OF LEUPROLIDE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | MATRIX LABORATORIES LTD (IN) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060004-A1 | Novel Process For The Preparation Of Leuprolide And Its Pharmaceutically Acceptable Salts Thereof | LPXN, GNRHR, VIP | KCNN4 699/4885KIF11 1406/4885KCNA3 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.