Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 17/20 | 0.42 |
| ▸ | IL1B | P01584 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755857 | 0.90 | P2RX7 (0.44) | P2RX7IL1BSLC6A4SLC6A3POLB | |
| SCHEMBL3756062 | 0.89 | P2RX7 (0.44) | P2RX7IL1BSLC6A4SLC6A3POLB | |
| SCHEMBL3741816 | 0.88 | P2RX7 (0.43) | P2RX7IL1BSLC6A4SLC6A3POLB | |
| SCHEMBL3738821 | 0.83 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL3742920 | 0.80 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL3738255 | 0.78 | P2RX7 (0.45) | P2RX7IL1BSLC6A4SLC6A3POLB | |
| SCHEMBL3748060 | 0.76 | P2RX7 (0.49) | P2RX7IL1BSLC6A4SLC6A3CHRNB2 | |
| SCHEMBL3754102 | 0.76 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL3751369 | 0.75 | DGAT1 (0.44) | P2RX7IL1B | |
| SCHEMBL3739009 | 0.75 | POLB (0.47) | P2RX7IL1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178865-B1 | 5-MEMBERED HETEROCYCLIC AMIDES AND RELATED COMPOUNDS | LUNDBECK H AS (DK) | 2015-08-19 | — | — | EP | disclosed |