Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014544 | 0.93 | PTGS1 (0.33) | ALOX5PTGS1PTGS2 | |
| SCHEMBL17014255 | 0.85 | — | — | |
| SCHEMBL21845221 | 0.77 | PTGS1 (0.38) | ALOX5PTGS1PTGS2 | |
| SCHEMBL13058874 | 0.75 | PTGS1 (0.33) | ALOX5PTGS1PTGS2 | |
| SCHEMBL21845219 | 0.72 | PTGS1 (0.40) | ALOX5PTGS1PTGS2 | |
| SCHEMBL17019676 | 0.69 | PDE7A (0.30) | — | |
| SCHEMBL24184947 | 0.69 | PTGS1 (0.33) | ALOX5PTGS1PTGS2 | |
| SCHEMBL15746194 | 0.68 | ALDH1A1 (0.35) | — | |
| SCHEMBL24184945 | 0.68 | PTGS1 (0.32) | ALOX5PTGS1PTGS2 | |
| SCHEMBL15746196 | 0.67 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | HAVCR2, SLC10A1, SORD | ALOX5 2894/4885PTGS1 1177/4885PTGS2 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.