⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014371 | 0.86 | BCL2L1 (0.32) | — | |
| SCHEMBL17014324 | 0.85 | BCL2L1 (0.36) | — | |
| SCHEMBL17014456 | 0.81 | BCL2L1 (0.36) | — | |
| SCHEMBL20152961 | 0.81 | — | — | |
| SCHEMBL17014350 | 0.79 | — | — | |
| SCHEMBL17014494 | 0.79 | BCL2L1 (0.36) | — | |
| SCHEMBL17014347 | 0.75 | LMNA (0.37) | — | |
| SCHEMBL17014328 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL17014457 | 0.73 | BCL2L1 (0.41) | — | |
| SCHEMBL17014368 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900656-B1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2017-05-17 | — | — | EP | disclosed |
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-08-20 | — | — | US | disclosed |
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-08-20 | — | — | US | disclosed |