SCHEMBL17014580

SCHEMBL17014580

c1ccc(-c2cc(-c3ccc(-c4ccc5c(c4)ncc4c6ccccc6ccc54)cc3)c(-c3ccccc3)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
RAB9A P51151 1/20 0.40
MET P08581 2/20 0.38
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
TNF P01375 1/20 0.33
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
CSF1R P07333 1/20 0.32
MAPK10 P53779 1/20 0.32
ALK Q9UM73 1/20 0.32
DHFR P00374 1/20 0.32
GPR3 P46089 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76389 0.78 ALDH1A1 (0.44) MAPTSMN1; SMN2NPC1LMNARAB9A
SCHEMBL17014578 0.77 ALDH1A1 (0.43) MAPTSMN1; SMN2NPC1LMNARAB9A
SCHEMBL2140937 0.76 ALDH1A1 (0.40) MAPTSMN1; SMN2RECQLCA12CA1
SCHEMBL16658500 0.76 ALDH1A1 (0.42) MAPTSMN1; SMN2LMNATNFKDM4E
SCHEMBL2733775 0.76 CYP11B1 (0.51) MAPTSMN1; SMN2RAB9ATNFKDM4E
SCHEMBL2158220 0.75 ALDH1A1 (0.47) MAPTSMN1; SMN2RAB9ATNFKDM4E
SCHEMBL2734767 0.75 BIRC5 (0.47) METCA12CA1CA2CA9
SCHEMBL2734772 0.74 TNF (0.44) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL24067936 0.74 CDK4 (0.39) MAPTMETCA12CA1CA2
SCHEMBL17014583 0.74 PIK3CA (0.40) MAPTLMNARECQLMETKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same LG CHEM, LTD. (KR) 2020-06-09 US disclosed
EP-2924020-B1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2019-01-16 EP disclosed
EP-2924020-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2015-09-30 EP disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same AFF2, ESR1, AFF4 MAPT 957/4885SMN1; SMN2 387/4885NPC1 3434/4885
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME AFF2, ESR1, AFF4 MAPT 957/4885SMN1; SMN2 387/4885NPC1 3434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.