SCHEMBL17014583

SCHEMBL17014583

c1ccc(-c2cc(-c3ccc(-c4ccc5nc(-c6ccccn6)cc(-c6ccccc6)c5c4)cc3)c(-c3ccccc3)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.40
KDM4E B2RXH2 3/20 0.36
MAPK1 P28482 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MET P08581 1/20 0.35
TOP1 P11387 4/20 0.35
CYP2C9 P11712 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17014605 0.88 CCR1 (0.42) KDM4EMAPK1ALDH1A1MAPTLMNA
SCHEMBL17014604 0.88 CCR1 (0.42) KDM4EMAPK1ALDH1A1MAPTLMNA
SCHEMBL16658502 0.85 GRM5 (0.41) PIK3CAKDM4EMAPK1ALDH1A1MAPT
SCHEMBL2733743 0.84 GRM5 (0.41) KDM4EMAPK1ALDH1A1MAPTLMNA
SCHEMBL16658479 0.82 GRM5 (0.43) KDM4EMAPK1ALDH1A1LMNACCR1
SCHEMBL16658498 0.81 GRM5 (0.40) KDM4EMAPK1ALDH1A1LMNATOP1
SCHEMBL20652907 0.79 MAPT (0.32) KDM4EMAPK1ALDH1A1MAPTMEN1
SCHEMBL19618368 0.79 DHODH (0.51) PIK3CAKDM4EMAPK1ALDH1A1MAPT
SCHEMBL19050388 0.78 PIK3CA (0.40) PIK3CAKDM4EMAPK1ALDH1A1MAPT
SCHEMBL76389 0.78 ALDH1A1 (0.44) KDM4EMAPK1ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same LG CHEM, LTD. (KR) 2020-06-09 US disclosed
EP-2924020-B1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2019-01-16 EP disclosed
EP-2924020-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2015-09-30 EP disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same AFF2, ESR1, AFF4 PIK3CA 3720/4885KDM4E 870/4885MAPK1 1899/4885
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME AFF2, ESR1, AFF4 PIK3CA 3720/4885KDM4E 870/4885MAPK1 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.