SCHEMBL1701464

SCHEMBL1701464

Oc1ccc2c(c1)CCC(O)C2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 1/20 0.65
DRD2 P14416 11/20 0.55
DRD3 P35462 11/20 0.55
DRD4 P21917 6/20 0.54
CYP19A1 P11511 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
ACHE P22303 2/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HTR1A P08908 1/20 0.47
ADRB2 P07550 1/20 0.47
CYP2D6 P10635 1/20 0.47
CASP1 P29466 1/20 0.47
LMNA P02545 2/20 0.46
MAPT P10636 1/20 0.46
DRD1 P21728 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2564622 0.92 DRD3 (0.65) OPRK1DRD2DRD3DRD4CYP19A1
SCHEMBL30199160 0.92 DRD3 (0.65) OPRK1DRD2DRD3DRD4CYP19A1
SCHEMBL29833729 0.83 DRD2 (0.52) OPRK1DRD2DRD3DRD4CYP19A1
SCHEMBL11824507 0.83 DRD2 (0.52) OPRK1DRD2DRD3DRD4CYP19A1
SCHEMBL6951077 0.82 CYP1A2 (0.49) OPRK1DRD2DRD3DRD4CYP1A2
SCHEMBL12410851 0.78 CYP1A2 (0.49) OPRK1DRD2DRD3DRD4CYP1A2
SCHEMBL6407573 0.78 CYP1A2 (0.49) OPRK1CYP1A2CYP11B1CYP11B2
SCHEMBL4621351 0.78 HTR1D (0.50) OPRK1DRD2DRD3CYP1A2CYP11B1
SCHEMBL6952592 0.78 HTR1D (0.50) OPRK1DRD2DRD3CYP1A2CYP11B1
SCHEMBL2892133 0.78 CYP1A2 (0.49) OPRK1CYP1A2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO claimed
WO-2024133361-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO claimed
WO-2023032466-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION DEVICE, ANTENNA, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAID LIQUID CRYSTAL COMPOSITION DIC株式会社 2023-03-09 WO claimed
WO-2022234709-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION DEVICE AND ANTENNA EACH USING SAME DIC株式会社 2022-11-10 WO claimed
WO-2021085280-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION DEVICE, AND ANTENNA DIC株式会社 2021-05-06 WO claimed
WO-2020121639-A1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE, AND POLYMERIZABLE COMPOUND DIC株式会社 2020-06-18 WO claimed
WO-2020116555-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC株式会社 2020-06-11 WO claimed
WO-2020115936-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC株式会社 2020-06-11 WO claimed
CN-110461852-A Liquid-crystal compounds and combinations thereof DAINIPPON INK & CHEMICALS 2019-11-15 CN claimed
CN-109804049-A Liquid-crystalline medium 默克专利股份有限公司 2019-05-24 CN claimed
CN-107108473-A Polymerizable compound and optically anisotropic body DIC株式会社 2017-08-29 CN claimed
CN-107108458-A Polymerizable compound and optically anisotropic body DIC株式会社 2017-08-29 CN claimed
CN-107108770-A Polymerizable composition, polymerizable composition and the optically anisotropic body using the polymerizable composition, polymerizable composition DIC株式会社 2017-08-29 CN claimed
CN-107108775-A Polymerizable composition, polymerizable composition and the optically anisotropic body using the polymerizable composition, polymerizable composition DIC株式会社 2017-08-29 CN claimed
CN-106715648-A Composition and liquid crystal display element using same DIC株式会社 2017-05-24 CN claimed
CN-105992970-A Liquid crystal display device having a plurality of pixel electrodes DIC株式会社 2016-10-05 CN claimed
CN-105960608-A Liquid crystal display device DIC株式会社 2016-09-21 CN claimed
US-20120097895-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2012-04-26 US claimed
US-5455325-A Optically active phenoxypropionic esters BASF AKTIENGESELLSCHAFT (DE) 1995-10-03 US claimed
US-4853149-A STABILITY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-08-01 US claimed