Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 12/20 | 0.65 |
| ▸ | DRD2 | P14416 | 11/20 | 0.65 |
| ▸ | DRD4 | P21917 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199160 | 1.00 | DRD3 (0.65) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL1701464 | 0.92 | OPRK1 (0.65) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL29833729 | 0.83 | DRD2 (0.52) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL11824507 | 0.83 | DRD2 (0.52) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL6958864 | 0.82 | HTR2A (0.46) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL6950358 | 0.78 | HTR1D (0.43) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL14037504 | 0.78 | DRD2 (0.44) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL10247150 | 0.78 | DRD3 (0.62) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL5722322 | 0.78 | DRD2 (1.00) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL5017850 | 0.78 | DRD2 (0.44) | DRD3DRD2DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| EP-2194035-B1 | Hydroxytetralones | SALTIGO GMBH (DE) | 2011-11-02 | — | — | EP | disclosed |
| EP-2194035-A2 | Hydroxytetralones | Saltigo GmbH (DE) | 2010-06-09 | — | — | EP | disclosed |
| JP-2000309554-A | PRODUCTION OF HYDROXY-SUBSTITUTED 2-TETRALOL | SUMITOMO CHEM CO LTD | 2000-11-07 | — | — | JP | disclosed |