Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723922 | 0.83 | CYP4F2 (0.35) | CYP4F2CYP4A11SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7033929 | 0.82 | — | — | |
| SCHEMBL9122775 | 0.81 | CYP4F2 (0.38) | CYP4F2CYP4A11SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29743352 | 0.81 | FDPS (0.40) | — | |
| SCHEMBL7243211 | 0.80 | SMN1; SMN2 (0.35) | CYP4F2CYP4A11SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL22551256 | 0.79 | FDPS (0.42) | — | |
| SCHEMBL29743378 | 0.79 | FDPS (0.42) | — | |
| SCHEMBL8529254 | 0.78 | FDPS (0.32) | ALDH1A1TSHR | |
| SCHEMBL11697387 | 0.77 | ACACB (0.38) | CYP4F2CYP4A11LMNAALDH1A1HSD17B10 | |
| SCHEMBL16013122 | 0.77 | ACACB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593552-A1 | RECOMBINANT HOST CELLS COMPRISING PHOSPHOKETOLASES | Butamax(tm) Advanced Biofuels LLC (US) | 2013-05-22 | — | — | EP | claimed |
| WO-2011159853-A1 | RECOMBINANT HOST CELLS COMPRISING PHOSPHOKETOLASES | BUTAMAX(TM) ADVANCED BIOFUELS LLC (US) | 2011-12-22 | — | — | WO | claimed |