SCHEMBL1702227

SCHEMBL1702227

CC1(C)OB(c2ccc3c(c2)c2cnccc2n3-c2ccccc2)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.40
LIPG Q9Y5X9 2/20 0.40
IRAK4 Q9NWZ3 1/20 0.38
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
DGAT1 O75907 1/20 0.33
EGFR P00533 1/20 0.33
ATM Q13315 1/20 0.33
TNKS O95271 1/20 0.33
CDK4 P11802 1/20 0.33
CDK6 Q00534 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
METAP2 P50579 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15945739 0.92 LPL (0.40) LPLLIPGIRAK4PRMT5WDR77
SCHEMBL30153711 0.89 LIPG (0.50) LPLLIPGIRAK4PRMT5WDR77
SCHEMBL4825950 0.89 LIPG (0.50) LPLLIPGIRAK4PRMT5WDR77
SCHEMBL31092481 0.88 CYP1A2 (0.43) LPLLIPGIRAK4PRMT5WDR77
SCHEMBL31503653 0.88 CYP1A2 (0.43) LPLLIPGIRAK4PRMT5WDR77
SCHEMBL18912470 0.86 CYP1A2 (0.42) LPLLIPGIRAK4PRMT5WDR77
SCHEMBL15945737 0.85 LIPG (0.48) LPLLIPGIRAK4PRMT5WDR77
SCHEMBL968588 0.85 LPL (0.42) LPLLIPGIRAK4KDM4EL3MBTL1
SCHEMBL527438 0.85 KDM4E (0.50) LPLLIPGIRAK4PRMT5WDR77
SCHEMBL29552630 0.85 KDM4E (0.50) LPLLIPGIRAK4PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011139129-A2 TRIPHENYLENE-BASED COMPOUND COMPRISING AN AROMATIC AMINE AND AN ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME 주식회사 두산 (KR) 2011-11-10 WO disclosed