Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10552626 | 0.88 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL422877 | 0.85 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL7196625 | 0.83 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL4368658 | 0.82 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL5681395 | 0.82 | TSHR (1.00) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1331857 | 0.82 | — | — | |
| SCHEMBL1330627 | 0.82 | — | — | |
| SCHEMBL11582291 | 0.82 | TSHR (1.00) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL15037 | 0.82 | — | — | |
| SCHEMBL420653 | 0.81 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10290390-B2 | Polymer blends | BOREALIS AG (AT) | 2019-05-14 | — | — | US | disclosed |
| EP-3107954-B1 | POLYMER BLENDS | BOREALIS AG (AT) | 2017-08-30 | — | — | EP | disclosed |
| US-20170011817-A1 | POLYMER BLENDS | BOREALIS AG (AT) | 2017-01-12 | — | — | US | disclosed |
| EP-2910595-A1 | Polymer Blends | Borealis AG (AT) | 2015-08-26 | — | — | EP | disclosed |