SCHEMBL422877

SCHEMBL422877

C=CC(=O)OCCCC.O=C(O)C1=CCC1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.63
HPGD P15428 1/20 0.63
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 1/20 0.46
ATM Q13315 1/20 0.45
HCAR2 Q8TDS4 3/20 0.44
THRB P10828 4/20 0.40
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
APP P05067 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PRKCA P17252 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL420653 0.96 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL423893 0.94 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL420649 0.94 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL424013 0.91 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL426844 0.88 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL426982 0.87 TSHR (0.45) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL7196625 0.86 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL17022326 0.85 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL10552626 0.85 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
Acrylic Acid Ethyl Ester SCHEMBL340906 0.85 TSHR (0.40) TSHRHPGDALDH1A1CYP3A4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940834-B2 Partially aromatic polyamide moulding compositions and their uses EMS-PATENT AG (CH) 2015-01-27 US claimed
EP-2410020-B1 Partially aromatic polyamide moulding compositions and their applications EMS PATENT AG (CH) 2013-01-30 EP claimed
US-20120022194-A1 PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES EMS-PATENT AG (CH) 2012-01-26 US claimed
EP-2789655-B1 POLYPHENYLENE SULFIDE RESIN COMPOSITION, MOLDED ARTICLE OF POLYPHENYLENE SULFIDE RESIN COMPOSITION, AND METHOD FOR PRODUCING POLYPHENYLENE SULFIDE RESIN COMPOSITION TORAY INDUSTRIES (JP) 2017-03-08 EP disclosed
US-8940834-B2 Partially aromatic polyamide moulding compositions and their uses EMS-PATENT AG (CH) 2015-01-27 US disclosed
EP-2789655-A1 POLYPHENYLENE SULFIDE RESIN COMPOSITION, MOLDED ARTICLE OF POLYPHENYLENE SULFIDE RESIN COMPOSITION, AND METHOD FOR PRODUCING POLYPHENYLENE SULFIDE RESIN COMPOSITION Toray Industries, Inc. (JP) 2014-10-15 EP disclosed
US-20130053177-A1 RESIN COMPOSITION FOR GOLF BALL AND GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-02-28 US disclosed
US-20120022194-A1 PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES EMS-PATENT AG (CH) 2012-01-26 US disclosed
US-20090253834-A1 ADHESIVE COMPOSITIONS USEFUL IN FLEXIBLE CIRCUIT SUBSTRATE APPLICATIONS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-10-08 US disclosed
EP-1549684-A4 IONOMER MODIFIED POLYPROPYLENE COMPOUND FOR SUPERIOR SCRATCH PERFORMANCE, LOW BLUSHING, AND MOLDED IN COLOR WITH CONTROLLABLE GLOSS SCHULMAN A INC (US) 2006-06-28 EP disclosed
EP-1549684-A2 IONOMER MODIFIED POLYPROPYLENE COMPOUND FOR SUPERIOR SCRATCH PERFORMANCE, LOW BLUSHING, AND MOLDED IN COLOR WITH CONTROLLABLE GLOSS A. Schulman Inc. (US) 2005-07-06 EP disclosed
EP-0564560-A1 COMPOSITIONS USEFUL IN THE MANUFACTURE OF GOLF BALLS. DU PONT (US) 1993-10-13 EP disclosed
EP-0341731-B1 THERMOPLASTIC ELASTOMERIC COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-22 EP disclosed
WO-1993016764-A1 PROCESS FOR THERMOPLASTIC GOLF BALLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-02 WO disclosed
WO-1992012206-A1 COMPOSITIONS USEFUL IN THE MANUFACTURE OF GOLF BALLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-23 WO disclosed
EP-0341731-A2 Thermoplastic elastomeric compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-15 EP disclosed
EP-0290588-A4 PARTIALLY GRAFTED THERMOPLASTIC COMPOSITIONS. DU PONT (US) 1989-09-11 EP disclosed
EP-0290588-A1 PARTIALLY GRAFTED THERMOPLASTIC COMPOSITIONS. DU PONT (US) 1988-11-17 EP disclosed
WO-1988003543-A1 PARTIALLY GRAFTED THERMOPLASTIC COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-19 WO disclosed
US-4353951-A Spot-weldable bonded clad metal plate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1982-10-12 US disclosed