Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544096 | 0.79 | ALOX5AP (0.41) | STIM1ORAI1GRIA2 | |
| SCHEMBL5299145 | 0.73 | TSHR (0.49) | SIRT6TSHRCHEK1CHEK2CHRNA7 | |
| SCHEMBL12156276 | 0.71 | STIM1 (0.56) | STIM1ORAI1RAB9ANPC1 | |
| SCHEMBL12241603 | 0.70 | RAB9A (0.55) | STIM1ORAI1KDM4ERAB9ANPC1 | |
| SCHEMBL12241607 | 0.70 | RAB9A (0.42) | STIM1ORAI1RAB9ANPC1PAX8 | |
| SCHEMBL12156265 | 0.70 | STIM1 (0.34) | STIM1ORAI1KDM4EHSD17B10RAB9A | |
| SCHEMBL12156279 | 0.69 | IL2 (0.56) | STIM1ORAI1RAB9ANPC1 | |
| SCHEMBL12155896 | 0.69 | STIM1 (0.60) | STIM1ORAI1RAB9ANPC1 | |
| SCHEMBL12155878 | 0.69 | RAB9A (0.47) | STIM1ORAI1RAB9ANPC1 | |
| SCHEMBL1701208 | 0.69 | ALOX5AP (0.38) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011139489-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-11-10 | — | — | WO | disclosed |