Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29747107 | 0.89 | CHEK2 (0.42) | TSHRCHRNA7CHEK2SIRT6OGA | |
| SCHEMBL31587136 | 0.84 | CHRNA7 (0.41) | TSHRCHRNA7CHEK1CHEK2NPC1 | |
| SCHEMBL1712176 | 0.83 | CHRNA7 (0.45) | TSHRCHRNA7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL103632 | 0.81 | CHRNA7 (0.47) | TSHRCHRNA7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5917985 | 0.77 | KDM4E (0.51) | CHRNA7LCKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18443469 | 0.74 | BACE1 (0.39) | TSHRCHRNA7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20270971 | 0.74 | BACE1 (0.39) | TSHRCHRNA7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5265516 | 0.74 | GABRA1 (0.48) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1702268 | 0.73 | SIRT6 (0.38) | TSHRCHRNA7CHEK1CHEK2SIRT6 | |
| SCHEMBL2507415 | 0.73 | CHRNA7 (0.41) | TSHRCHRNA7OGANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |