Propanil

Propanil

SCHEMBL1702271

CCC(=O)Nc1ccc(Cl)c(Cl)c1.CCC(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 1.00
TSHR P16473 1/20 0.73
EPHX1 P07099 1/20 0.63
EPHX2 P34913 1/20 0.63
ALDH1A1 P00352 3/20 0.63
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
L3MBTL1 Q9Y468 1/20 0.60
HDAC3 O15379 1/20 0.60
HDAC4 P56524 1/20 0.60
HDAC1 Q13547 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC2 Q92769 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC8 Q9BY41 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60
HDAC5 Q9UQL6 1/20 0.60
MAPT P10636 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propanil SCHEMBL26871 1.00 CYP3A4 (1.00) CYP3A4TSHREPHX1EPHX2ALDH1A1
Propanil SCHEMBL21900164 1.00 CYP3A4 (1.00) CYP3A4TSHREPHX1EPHX2ALDH1A1
Propanil SCHEMBL8983219 0.98 CYP3A4 (0.96) CYP3A4TSHREPHX1EPHX2ALDH1A1
Propanil SCHEMBL634840 0.98 CYP3A4 (0.96) CYP3A4TSHREPHX1EPHX2ALDH1A1
Propanil SCHEMBL19358624 0.91 CYP3A4 (0.82) CYP3A4TSHREPHX1EPHX2ALDH1A1
SCHEMBL11865051 0.87 CYP3A4 (0.75) CYP3A4TSHRALDH1A1KMT2AMEN1
SCHEMBL14426539 0.86 CYP3A4 (0.75) CYP3A4TSHRALDH1A1KMT2AMEN1
SCHEMBL3674141 0.86 CYP3A4 (0.75) CYP3A4EPHX1EPHX2ALDH1A1KMT2A
SCHEMBL12796807 0.86 CYP3A4 (0.75) CYP3A4TSHREPHX2ALDH1A1KMT2A
SCHEMBL15302068 0.84 TSHR (1.00) CYP3A4TSHRALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689328-B2 Crystalline modification of propanil UPL LIMITED (IN) 2020-06-23 US disclosed
US-20190248734-A1 CRYSTALLINE MODIFICATION OF PROPANIL UPL LIMITED 2019-08-15 US disclosed
US-10336685-B2 Crystalline modification of propanil UPL LIMITED (IN) 2019-07-02 US disclosed
US-20170369423-A1 CRYSTALLINE MODIFICATION OF PROPANIL UPL LIMITED (IN) 2017-12-28 US disclosed
EP-3247698-A1 CRYSTALLINE MODIFICATION OF PROPANIL UPL Limited (IN) 2017-11-29 EP disclosed
WO-2016116797-A1 CRYSTALLINE MODIFICATION OF PROPANIL UPL LIMITED (IN) 2016-07-28 WO disclosed
EP-2701747-A2 HSP90 COMBINATION THERAPY Sloan-Kettering Institute for Cancer Research (US) 2014-03-05 EP disclosed
US-20130210630-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (DE) 2013-08-15 US disclosed
WO-2012149493-A2 HSP90 COMBINATION THERAPY SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2012-11-01 WO disclosed
WO-2012003441-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (US) 2012-01-05 WO disclosed
US-5250499-A Delivery system for agricultural chemicals ISP INVESTMENTS INC. (US) 1993-10-05 US disclosed
US-5176736-A Emulsifiable herbicide concentrate ISP INVESTMENTS INC. (US) 1993-01-05 US disclosed
US-5160528-A Stable emulsifiable herbicide concentrates ISP INVESTMENTS INC. (US) 1992-11-03 US disclosed
US-5156666-A Emulsifiable concentrate comprising a pesticide, a surfactant, a hydrophobic solvent and a hydrophilic solvent; storage stability ISP INVESTMENTS INC. (US) 1992-10-20 US disclosed
EP-0505378-A1 DELIVERY SYSTEM FOR AGRICULTURAL CHEMICALS ISP INVESTMENTS INC. (US) 1992-09-30 EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed
WO-1992004827-A1 HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 WO disclosed
US-5071463-A Stable, emulsifiable concentrate of an herbicide and pyrrolido ne derivative; dispersibility ISP INVESTMENTS INC. (US) 1991-12-10 US disclosed
WO-1990012012-A1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-18 WO disclosed
EP-0019796-A1 Propionic acid esters, preparation of these compounds, herbicides containing these compounds as active substances, and the use of such compounds and agents for combating weeds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210630-A1 SELF-EMULSIFYING OIL PHOSPHO1, SQLE, ALOX15 CYP3A4 3856/4885TSHR 4755/4885EPHX1 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.