SCHEMBL3674141

SCHEMBL3674141

CCCC(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.75
ALDH1A1 P00352 2/20 0.74
MEN1 O00255 1/20 0.74
LMNA P02545 1/20 0.74
HPGD P15428 1/20 0.74
KMT2A Q03164 1/20 0.74
L3MBTL1 Q9Y468 1/20 0.66
ESRRA P11474 1/20 0.63
TP53 P04637 1/20 0.61
EPHX1 P07099 1/20 0.59
EPHX2 P34913 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
MAPK1 P28482 1/20 0.58
HDAC3 O15379 1/20 0.57
HDAC4 P56524 1/20 0.57
HDAC1 Q13547 1/20 0.57
HDAC7 Q8WUI4 1/20 0.57
HDAC2 Q92769 1/20 0.57
HDAC10 Q969S8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1876366 0.89 L3MBTL1 (0.69) CYP3A4ALDH1A1MEN1LMNAHPGD
SCHEMBL1878130 0.88 CYP3A4 (0.67) CYP3A4ALDH1A1MEN1LMNAHPGD
SCHEMBL8671223 0.87 L3MBTL1 (0.68) CYP3A4ALDH1A1MEN1LMNAHPGD
SCHEMBL1874109 0.87 L3MBTL1 (0.68) CYP3A4ALDH1A1MEN1LMNAHPGD
SCHEMBL1878693 0.87 L3MBTL1 (0.68) CYP3A4ALDH1A1MEN1LMNAHPGD
SCHEMBL1884667 0.87 L3MBTL1 (0.68) CYP3A4ALDH1A1MEN1LMNAHPGD
SCHEMBL29696201 0.87 TP53 (0.73) CYP3A4ALDH1A1MEN1LMNAHPGD
SCHEMBL14886138 0.87 ALDH1A1 (0.70) CYP3A4ALDH1A1MEN1LMNAHPGD
Propanil SCHEMBL1702271 0.86 CYP3A4 (1.00) CYP3A4ALDH1A1MEN1LMNAKMT2A
SCHEMBL15107476 0.86 L3MBTL1 (0.74) CYP3A4ALDH1A1MEN1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0835605-A1 Phenylamides as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP claimed
US-20230146507-A1 N-PHENYL-3-MERCAPTOPROPANAMIDE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2023-05-11 US disclosed
EP-2180790-A2 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES Dow AgroSciences LLC (US) 2010-05-05 EP disclosed
WO-2009029518-A2 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES DOW AGROSCIENCES LLC (US) 2009-03-05 WO disclosed
US-5833742-A APPLYING ONTO OR INTO MARINE STRUCTURE A MICROBIOCIDES TO INHIBIT THE ORGANISM GROWTH ROHM AND HAAS COMPANY (US) 1998-11-10 US disclosed
EP-0835605-A1 Phenylamides as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146507-A1 N-PHENYL-3-MERCAPTOPROPANAMIDE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS MGAM, PREP, MME CYP3A4 236/4885ALDH1A1 253/4885MEN1 2106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.