Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 12/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126291 | 0.86 | FGFR3 (0.67) | FGFR3GAAKDM4E | |
| SCHEMBL17023040 | 0.85 | FGFR3 (0.55) | FGFR3 | |
| SCHEMBL17023145 | 0.84 | FGFR3 (0.62) | FGFR3LMNASGMS2NOTUM | |
| SCHEMBL17023083 | 0.82 | FGFR3 (0.52) | FGFR3 | |
| SCHEMBL17023042 | 0.82 | FGFR3 (0.61) | FGFR3KDM4EKMT2A | |
| SCHEMBL17023055 | 0.82 | FGFR3 (0.57) | FGFR3GAAKDM4EKMT2A | |
| SCHEMBL17023087 | 0.81 | FGFR3 (0.81) | FGFR3LMNA | |
| SCHEMBL17023119 | 0.80 | FGFR3 (0.76) | FGFR3 | |
| SCHEMBL17023153 | 0.80 | FGFR3 (0.58) | FGFR3GAAKMT2A | |
| SCHEMBL17023169 | 0.80 | FGFR3 (0.54) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |