Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 16/20 | 0.62 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126555 | 0.88 | FGFR3 (0.76) | FGFR3 | |
| SCHEMBL17023102 | 0.87 | FGFR3 (0.79) | FGFR3 | |
| SCHEMBL17023058 | 0.85 | FGFR3 (0.79) | FGFR3 | |
| SCHEMBL17023014 | 0.84 | FGFR3 (0.54) | FGFR3SGMS2LMNANOTUM | |
| SCHEMBL17023099 | 0.84 | FGFR3 (0.79) | FGFR3 | |
| SCHEMBL1126124 | 0.77 | FGFR3 (0.72) | FGFR3FGFR4 | |
| SCHEMBL1126358 | 0.77 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL17023087 | 0.76 | FGFR3 (0.81) | FGFR3LMNA | |
| SCHEMBL12678203 | 0.75 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL17023093 | 0.75 | FGFR3 (0.55) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |