Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 19/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023031 | 0.90 | FGFR3 (0.65) | FGFR3 | |
| SCHEMBL17023062 | 0.89 | FGFR3 (0.66) | FGFR3MAPT | |
| SCHEMBL1126244 | 0.89 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL17023115 | 0.89 | FGFR3 (0.67) | FGFR3 | |
| SCHEMBL17023101 | 0.89 | FGFR3 (0.64) | FGFR3 | |
| SCHEMBL17023067 | 0.87 | FGFR3 (0.65) | FGFR3TP53 | |
| SCHEMBL17023176 | 0.85 | FGFR3 (0.80) | FGFR3 | |
| SCHEMBL17023138 | 0.82 | FGFR3 (0.67) | FGFR3 | |
| SCHEMBL17023167 | 0.82 | FGFR3 (0.69) | FGFR3 | |
| SCHEMBL17023181 | 0.81 | FGFR3 (0.59) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |