Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 12/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126852 | 0.88 | FGFR3 (0.66) | FGFR3KDR | |
| SCHEMBL17023093 | 0.84 | FGFR3 (0.55) | FGFR3KDRHRH3 | |
| SCHEMBL17023167 | 0.83 | FGFR3 (0.69) | FGFR3 | |
| SCHEMBL17023067 | 0.81 | FGFR3 (0.65) | FGFR3 | |
| SCHEMBL17023154 | 0.81 | FGFR3 (0.65) | FGFR3KDRHTR2AHTR2C | |
| SCHEMBL17023040 | 0.81 | FGFR3 (0.55) | FGFR3 | |
| SCHEMBL17023062 | 0.81 | FGFR3 (0.66) | FGFR3KDR | |
| SCHEMBL17023066 | 0.79 | FGFR3 (0.78) | FGFR3KDR | |
| SCHEMBL17023105 | 0.79 | FGFR3 (0.79) | FGFR3 | |
| SCHEMBL17023138 | 0.79 | FGFR3 (0.67) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |